An innovative wound dressing material or Germguard infused with natural ingredients for the Thailand community

Throughout the last few years, the development of the integrated medical industry called Medical Hub,

which is an industry group that uses new technologies and innovations as a mechanism to drive the economy in the future (New S-Curve) according to the Thailand 4.0 policy, has created Cooperation between government and private agencies. Thailand’s policy calls for collaboration between the government and various private sector, which includes small and medium-sized firms, business groups, and communities, in order to establish a complete health care industry related to medical hub. Significant investments in research, medical device manufacture, the development of standardized medications and medical supplies, as well as staff development, will be required in the future to construct new outputs. However, to really fulfill requirements, it is necessary to overcome limitations posed by past technologies and products. Additionally, the key source of concern for the medical industry is the continued high cost of imported medical equipment and supplies resulting from Thailand’s difficulty to build a large-scale manufacturing base. Furthermore, we would like to explicitly enhance local communities in Thailand’s areas make a profit.

Due to the variety of natural extracts available locally in Thailand with medicinal efficacy,this is the starting point

for driving the value of these raw materials into medical applications such as wound dressing. For instance, mangosteen peel extract contains an essential component known as “Xantone”, which has therapeutic benefits such as anti-infection, anti-tumor cell, antioxidants, disinfection, and especially antibacterial. We used our experience in the selection of proper materials to combine with these chemicals to obtain satisfactory goods on behalf of a Research Unit on Herbal Extract-Infused Advanced Wound Dressing at Chulalongkorn University’s Petroleum and Petrochemical College. Over this, it may be possible to create an innovative wound dressing containing natural extracts that could be used in place of imported dressings in the years ahead.

Giving GermGuard goods to Somdej Phra Pinklao Hospital's Surgical Examination Room in order to assist needy patients on January 20 and October 24, 2020.
Germguard products are applied to patients at Sanpatong Hospital in Chiang Mai Province, as well as to popularize the wound management training program at Yasothon Hospital on September 14-18, 2020.
Indeed, the assumptions of the study are based on past concerns regarding the previous products which are poor

adsorption, antimicrobial longevity, pressure withstand, and antimicrobial resistance. Our Research unit with “Germguard” technology, which extends the life of the material and could resist invading germs, making the dressing more stable to be stored while keeping high antibacterial efficacy that superior to prior technologies. Likewise, using sponge-like porous material instead of thin-layer dressing will help to absorb some exudate excreted from the wound and utilize under pressure. This novel product is also known as “Xanfoam” containing the natural active agent. Additionally, Thailand’s National Metal and Materials Technology Center (MTEC) assured Xanfoam in the sterilizing efficiency test, demonstrating the potential for bacterial suppression. And also, the research in animals and volunteer patients (Clinical Trial) were collaborated from faculty of Medicine and faculty of Veterinary Science, Chulalongkorn University.

Germguard XanFoam products were used to treat a carbuncle in a polio patient who had been scalded with hot boiled water, infected, and healed till the wound healed completely. (August 2020 – April 2021)
Utilization of Germguard XanFoam products in the treatment of carbuncle. (September 2020 - April 2021)
Germguard XanFoam use in patient with chronic venous leg disease. (March 23 - April 20, 2020)

In addition, the prototype products were donated to people who had suffered serious injuries and were being treated in hospitals such as Sanpatong Hospital in Chiang Mai Province and Somdet Phra Pinklao Hospital in Bangkok for their benefit. The results from the patients indicated that the treatment was beneficial in wound recovery, such as faster wound healing or reduction of biofilm formed by infection. Additionally, the research team advanced the prototype work in order to win the prize, which resulted in a later innovation award contest. It is extremely delighted that the Germguard products developed by the research team have received numerous government awards. This is an illustration of a problem-solving effort of our research team resulting in the medical business’s long-term growth.

Our first prototype was awarded the first runner-up prize for research prototypes of non-food agricultural items (Non-food product) on May 16, 2019.
Receiving the second runner-up award for the National Innovation in Society and Environment for the year 2020 on October 5, 2020.